Publications Team 2 – INSERM UMR 1033

Bone, Cancers and Metastases

Top 10 publications over the past 5 years


  1. PANTANO F, CROSET M, DRIOUCH K, BEDNARZ-KNOLL N, IULIANI M, RIBELLI G, BONNELYE E, WIKMAN H, GERACI S, BONIN F, SIMONETTI S, VINCENZI B, HONG SS, SOUSA S, PANTEL K, TONINI G, SANTINI D, CLEZARDIN P. Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions. Oncogene. 2021;40(7):1284-1299. doi: 10.1038/s41388-020-01603-6
  2. PUPPO M, TAIPALENMÄKI H, HESSE E, CLÉZARDIN P. Non-coding RNAs in bone remodelling and bone metastasis: Mechanisms of action and translational relevance. Br J Pharmacol. 2021;178(9):1936-1954. doi: 10.1111/bph.14836
  3. CLEZARDIN P, COLEMAN R, PUPPO M, OTTEWELL P, BONNELYE E, PAYCHA F, CONFAVREUX CB, HOLEN I. Bone Metastasis: Mechanisms, Therapies and Biomarkers. Physiol Rev. 2021;101(3):797-855. doi: 10.1152/physrev.00012.2019
  4. BELLANGER A, LE DT, VENDRELL J, WIERINCKX A, PONGOR LS, SOLASSOL J, LACHUER J, CLEZARDIN P, GYÖRFFY B, COHEN PA. Exploring the Significance of the Exon 4-Skipping Isoform of the ZNF217 Oncogene in Breast Cancer. Front Oncol. 2021;11:647269. doi: 10.3389/fonc.2021.647269.

  5. BOUCHET M, LAINÉ A, BOYAULT C, PROPONNET-GUERAULT M, MEUGNIER E, BOUAZZA L, KAN CWS, GERACI S, EL-MOGHRABI S, HERNANDEZ-VARGAS H, BENETOLLO C, YOSHIKO Y, DUTERQUE-COQUILLAUD M, CLÉZARDIN P, MARIE JC, BONNELYE E. ERRα expression in bone metastases leads to an exacerbated anti-tumor immune response. Cancer Res. 2020; 80(13):2914-2926. doi: 10.1158/0008-5472.
  6. DONINI CF, El HELOU M, WIERINCKX A, GYÖRFFY B, AIRES S, ESCANDE A, CROZE S, CLEZARDIN P, LACHUER J, DIAB-ASSAF M, GHAYAD SE, FERVERS B, CAVAILLÈS V, MAGUER-SATTA V, COHEN PA. Long-Term Exposure of Early-Transformed Human Mammary Cells to Low Doses of Benzo[a]pyrene and/or Bisphenol A Enhances Their Cancerous Phenotype via an AhR/GPR30 Interplay. Front Oncol. 2020; 10:712. doi: 10.3389/fonc.2020.00712.
  7. VARGAS G, BOUCHET M, BOUAZZA L, REBOUL P, BOYAULT C, GERVAIS M, KAN C, BENETOLLO C, BREVET M, CROSET M, MAZEL M, CAYREFOURCQ L, GERACI S, VACHER S, PANTANO F, FILIPITS M, DRIOUCH K, BIECHE I, GNANT M, JACOT W, AUBIN JE, DUTERQUE-COQUILLAUD M, ALIX-PANABIÈRES C, CLÉZARDIN P, BONNELYE E. ERRα promotes breast cancer cell dissemination to bone by increasing RANK expression in primary breast tumors. Oncogene. 2019; 38(7):950-964. doi: 10.1038/s41388-018-0579-3.
  8. CROSET M, PANTANO F, KAN CWS, BONNELYE E, DESCOTES F, ALIX-PANABIÈRES C, LECELLIER CH, BACHELIER R, ALLIOLI N, HONG SS, BARTKOWIAK K, PANTEL K, CLÉZARDIN P. MicroRNA-30 family members inhibit breast cancer invasion, osteomimicry, and bone destruction by directly targeting multiple bone metastasis-associated genes. Cancer Res. 2018; 78(18):5259-5273. doi: 10.1158/0008-5472.CAN-17-3058.
  9. BELLANGER A, DONINI CF, VENDRELL JA, LAYAUD J, MACHUCA-GAYET I, RUEL M, VOLLAIRE J, GRISARD E, GYÖFFY B, BIÈCHE I, PEYRUCHAUD O, COLL JL, TREILLEUX I, MAGUER-SATTA V, JOSSERAND V, COHEN PA. The critical role of the ZNF217 oncogene in promoting breast cancer metastasis to the bone. J Pathol. 2017; 242(1):73-89. doi: 10.1002/path.4882.
  10. REYNAUD C, FERRERAS L, DI MAURO P, KAN C, CROSET M, BONNELYE E, PEZ F, THOMAS C, AIMONT G, KARNOUB AE, BREVET M, CLEZARDIN P. Lysyl oxidase is a strong determinant of tumor cell colonization in bone. Cancer Res. 2017; 77(2):268-278. doi: 10.1158/0008-5472.CAN-15-2621.

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